Paradoxical Relationship Between Cannabis Use and Arrhythmia Risk
Researchers investigated the relationship between cannabis use and arrhythmia risk in patients with and without heart disease.
Cannabis use and arrhythmias have a paradoxical relationship, where cannabis use increases arrhythmia risk in the general population but lowers risk among patients with heart disease, according to a study presented at the Heart Failure Society of America (HFSA) Annual Scientific Meeting 2025.
- The study was held from September 26 to 29, 2025, in Minneapolis, Minnesota.
- Investigators searched publication databases through February 2025 for relevant studies.
- A total of 21 observational studies were included in this systematic review and meta-analysis.
The relationship between cannabis and arrhythmias has not been fully established, and some conflicting evidence about whether cannabis may be harmful or protective have been published.
Author's summary: Cannabis use has a paradoxical relationship with arrhythmia risk.