Heart Health: Long-Term Melatonin Use Linked to Cardiovascular Risk
New research indicates that individuals with insomnia who take melatonin supplements for over a year face an increased risk of heart failure compared to those who do not use this common sleep aid.
Study Findings and Presentation
The researchers found that long-term melatonin users were more likely to be diagnosed with heart failure, hospitalized for the condition, or die from any cause. These findings were shared at the American Heart Association’s Scientific Sessions 2025 in New Orleans.
“Melatonin supplements may not be as harmless as commonly assumed.”
This preliminary study has yet to be published in a peer-reviewed journal.
Research Limitations and Safety Concerns
The researchers emphasized that their study does not prove a direct cause-and-effect link between melatonin use and heart failure risk. Nonetheless, the results raise concerns about the safety of prolonged melatonin supplementation and suggest a need for more thorough cardiovascular safety evaluations.
Regulatory and Usage Issues
- Many melatonin supplements are available over-the-counter without a prescription.
- These products are not regulated, allowing people to use them without medical guidance.
Such unregulated use highlights the importance of awareness regarding potential risks.
Author’s Summary
Extended melatonin supplement use may increase cardiovascular risks, underscoring the need for cautious use and further research on its long-term safety.