New study links melatonin and heart failure, but experts say don’t panic yet

New Study Links Melatonin and Heart Failure

A recent study analyzing health records of tens of thousands of adults with chronic insomnia found that those prescribed melatonin for over a year had a greater risk of heart failure within five years compared to nonusers, according to the American Heart Association.

Study Findings

Long-term melatonin users showed a higher likelihood of hospitalization due to heart failure.
They also had an increased risk of death from any cause relative to nonusers.

Expert Reactions

The study has not yet been peer-reviewed and has elicited cautious responses from sleep medicine specialists and cardiologists.

Experts urge the public not to panic and emphasize the need for further research on prolonged melatonin use.

Contradictions and Conference Presentation

These preliminary results seem to contradict earlier research hinting at melatonin's potential benefits for heart failure patients. The findings will be presented at the American Heart Association’s Scientific Sessions, a prominent cardiovascular research conference.

Additional Notes

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Author's Summary

This emerging study raises concerns about long-term melatonin use and heart failure risk, but experts caution against early conclusions and call for more research.

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Toronto Sun — 2025-11-07