New research suggests that long-term use of melatonin supplements may increase the risk of heart failure, particularly in people with insomnia.
Researchers found that individuals who used melatonin for more than a year were more likely to be diagnosed with heart failure, require hospitalization, or die from any cause.
The study's findings will be presented at the American Heart Association's Scientific Sessions 2025 meeting in New Orleans, although the research has not yet been published in a peer-reviewed scientific journal.
Long-term use of melatonin supplements may increase the risk of heart failure.
Author's summary: Melatonin use linked to heart failure risk.